Extreme exercise linked to blood poisoning / Possible Solution
The Impact of a 24-h Ultra-Marathon on Circulatory Endotoxin and Cytokine Profile. International Journal of Sports Medicine, 2015; DOI: 10.1055/s-0034-1398535
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The nutriceutical, bovine colostrum, truncates the increase in gut permeability caused by heavy exercise in athletes. Am J Physiol Gastrointest Liver Physiol. 2011 Mar;300(3):G477-84. doi: 10.1152/ajpgi.00281.2010. Epub 2010 Dec 9
Highlights
Individuals who take part in extreme endurance events, especially in the heat and with little training, put their bodies under enormous strain above the body’s protective capacity. With elevated levels of endotoxins in the blood, the immune system’s response can be far greater than the body’s protective counter-action. In extreme cases, it leads to sepsis induced systemic inflammatory response syndrome, which can be fatal if it is not diagnosed and treated promptly.
“Blood samples taken before and after the events, compared with a control group, proved that exercise over a prolonged period of time causes the gut wall to change, allowing the naturally present bacteria, known as endotoxins, in the gut to leak into the bloodstream. This then triggers a systemic inflammatory response from the body’s immune cells, similar to a serious infection episode.
“Nearly all of the participants in our study had blood markers identical to patients admitted to hospital with sepsis. That’s because the bacterial endotoxins that leach into the blood as a result of extreme exercise, triggers the body’s immune cells into action.”
Significantly the study found that individuals who are fit, healthy and follow a steady training program to build up to extreme endurance events, develop immune mechanisms to counteract this, without any side effects.
The Possible Solution
Scientists investigating natural ways to enhance athletic performance have found that bovine colostrum can massively reduce gut permeability — otherwise known as ‘leaky gut syndrome.’ Their findings, published in the March issue of the American Journal of Physiology-Gastrointestinal and Liver Physiology, could have positive implications not just for athletes but also for sufferers of heatstroke.
A research group led by Ray Playford, Professor of Medicine at Barts and The London School of Medicine and Dentistry looked at athletes who were asked to run for 20 minutes at 80 per cent of their aerobic maximum. At the end of the exercise, changes in the subjects gut leakiness were measured using urine sample — also determined were changes in the athletes’ core temperature. Under standard conditions, gut leakiness had increased by 250 per cent and temperature had risen by 2 degrees. However, when the group were given a drink of dairy colostrum for two weeks before the trial, the rise in gut leakiness was reduced by about 80 per cent, despite the same effort and temperature rise.
“Blood samples taken before and after the events, compared with a control group, proved that exercise over a prolonged period of time causes the gut wall to change, allowing the naturally present bacteria, known as endotoxins, in the gut to leak into the bloodstream. This then triggers a systemic inflammatory response from the body’s immune cells, similar to a serious infection episode.
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Video Clip was from: Trails in Motion en México, Cine de Trail Running 2015 CC ( Which looks AMAZING !!! )