Natural compound in basil may protect against Alzheimer’s
Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer’s disease pathology, a preclinical study suggests. The team discovered a sensing mechanism associated with the gut microbiome that explains how fenchol reduces neurotoxicity in the Alzheimer’s brain.
Atefeh Razazan, Prashantha Karunakar, Sidharth P. Mishra, Shailesh Sharma, Brandi Miller, Shalini Jain and Hariom Yadav. Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis. Frontiers in Aging Neuroscience, 2021 DOI: 10.3389/fnagi.2021.735933
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