Choline may affect muscle responses to RET through many potential mechanisms. Since choline is a precursor to a neurotransmitter, ACh, which relays a signal from motor neurons to skeletal muscle to contract and generate force, and of which synthesis is reported to be affected by availability of choline [36,37], insufficient choline consumption may limit the availability of ACh at the neuromuscular junction (NMJ) and, in turn, muscle contraction and force generation.
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Lee, C. W., Lee, T. V., Galvan, E., Chen, V. C., Bui, S., Crouse, S. F., Fluckey, J. D., Smith, S. B., & Riechman, S. E. (2023). The Effect of Choline and Resistance Training on Strength and Lean Mass in Older Adults. Nutrients, 15(18), 3874. https://doi.org/10.3390/nu15183874
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