A major randomized controlled trial, the COSMOS study, previously established a stunning statistic: older adults taking daily cocoa extract experienced a 27% reduction in cardiovascular disease death. However, the biological reason why remained unclear—until now. A new analysis published in Age and Ageing (Sept 2025) examined the bloodwork of 598 participants over two years. The researchers discovered that the cocoa extract (containing 500mg of flavanols) significantly reduced “inflammaging”—specifically lowering high-sensitivity C-reactive protein (hsCRP) by 8.4%. This reduction in chronic inflammation offers the “missing link” that explains the mechanism behind the massive 27% drop in cardiovascular mortality.
- Citations & Resources
- Primary Study: Li, S., et al. “Effects of 2-year cocoa extract supplementation on inflammaging biomarkers in older US adults.” Age and Ageing, 2025. Link to Article
- Press Release: Mass General Brigham. “Study finds cocoa extract supplement reduced key marker of inflammation and aging.” EurekAlert! Link to Press Release
- Disclaimers
- “This information is for educational purposes only and should not be interpreted as medical advice.”
- “The study discussed was conducted on older adults (60+). Further research may be needed to confirm these findings in other populations.”
- “Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.”
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