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PCB cocktails for two: Effects Second Generation

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Re-Post for filing 2008

Contact: Judith Jansen
bor2@ssr.org
608-256-2777
Society for the Study of Reproduction

 

Since the 1962 publication of Silent Spring by Rachel Carson, awareness of how environmental toxicants can impact fertility has increased. In an article on p. 1091 of this issue, Steinberg and colleagues provide evidence that adverse reproductive effects of toxicants may extend not only to the children of exposed individuals, but also to the next generation. They treated pregnant rats with a mixture of polychlorinated biphenyls (PCBs) and found that reproductive markers were disrupted not only in the female offspring of these rats, but also in the “grand offspring,” which are derived from oocytes present in fetuses of the treated females. Changes in the second generation included blunting of preovulatory LH release, reduced progesterone concentrations and reduced uterine weights. The use of low doses of PCBs in this study increases the potential relevance of these findings to reproductive health.

About Post Author

Ralph Turchiano

I have a strong affinity for the sciences which led me to create my sites. My compulsion for the past decade has been reviewing literally every peer-reviewed research article. Which can easily be validated by following my posts. To me, science is where the real news is, as it will mold our destiny beyond that of politics or economics. 😉 Please feel free to e-mail: 161803p314159@gmail.com
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