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Natural compound in basil may protect against Alzheimer’s

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer’s disease pathology, a preclinical study suggests. The team discovered a sensing mechanism associated with the gut microbiome that explains how fenchol reduces neurotoxicity in the Alzheimer’s brain.

#Fenchol #dementia #basil

Atefeh Razazan, Prashantha Karunakar, Sidharth P. Mishra, Shailesh Sharma, Brandi Miller, Shalini Jain and Hariom Yadav. Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis. Frontiers in Aging Neuroscience, 2021 DOI: 10.3389/fnagi.2021.735933

Amyloid, amyloid beta protein, fenchol,  Alzheimer’s , basil, natural, Aβ, proteolysis, FFAR2, neurotoxicity, dementia, spices, plant compounds, SCFAs, Short chain fatty acids, gut microbiome, plaque, AD pathology, amyloid-beta, neurotoxicity,

#Fenchol #dementia #basil #alzheimer’s #amyloid #FFAR2 #SCFA #microbiome

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