Month: November 2021

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Reinfection with SARS-CoV-2: outcome, risk factors and vaccine efficacy in a Scottish cohort Quote”he rate of detected reinfection after two doses of vaccine was 1.35 (95% CI 1.02 to 1.78) times higher in those vaccinated before first infection than in those unvaccinated at first infection. “

Abstract Background -- The objective of this study was to investigate how protection against COVID-19 conferred by previous infection is modified by vaccination. Methods -- In a cohort of all…

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Immune imprinting and SARS-CoV-2 vaccine design- quote” This suggests that pre-existing crossreactive antibodies to Spike can limit new antibody responses to Spike from different viral strains (i.e., hCoVs and SARS-CoV-2); this is consistent with a potential problem of immune imprinting between ancestral and variant strains of SARS-CoV-2.

Reformulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines with variant strains is being pursued to combat the global surge in infections. We hypothesize that this may be suboptimal due…

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Transmission potential of vaccinated and unvaccinated persons infected with the SARS-CoV-2 Delta variant in a federal prison, July-August 2021 – ” As this field continues to develop, clinicians and public health practitioners should consider vaccinated persons who become infected with SARS-CoV-2 to be no less infectious than unvaccinated persons”

Abstract Background The extent to which vaccinated persons who become infected with SARS-CoV-2 contribute to transmission is unclear. During a SARS-CoV-2 Delta variant outbreak among incarcerated persons with high vaccination…

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