Public release date: 6-Nov-2007

Concord grape juice and red wine polyphenols show promise in counteracting beta-amyloid plaques associated with cognitive decline

Two recent population studies associated moderate red wine and 100 percent fruit juice consumption with lowering the risk of AD dementia (wine) or delay in AD onset (juice). Adding further weight to those studies is the research presented by Dr. Lap Ho at Neuroscience 2007, which demonstrated the potentially protective effect of Concord grape juice and Cabernet Sauvignon polyphenols to slow beta-amyloid neuropathology.

Previous work by Dr. Pasinetti’s group at MSSM reported that moderate consumption of Cabernet Sauvignon wine had reduced AD-type neuropathology and prevented cognitive decline in a transgenic mouse model , yet counseled that even moderate intake of alcohol may carry health risks, particularly with an older population