Public release date: 6-Dec-2007
Rio de Janeiro, Brazil – — A new study recently published in the Journal of Cosmetic Dermatology reports on the discovery of caffeine’s novel benefit in slenderizing thighs.
The Brazilian researchers studied 99 women treated with a cream consisting mostly of a 7 percent caffeine solution. The women used the cream twice daily for 30 days.
When the researchers took their subjects’ measurements at the end of the study, the slimming effect was clear. More than 80 percent of the women had a reduction in the circumference of their upper and lower thighs. Nearly 68 percent also reduced their hip measurements.
Whether caffeine banishes cellulite is less clear. The researchers assessed cellulite changes with a handheld imaging instrument that reveals microcirculation in fat tissue. Imaging showed little change in cellulite even in the hips and thighs that slimmed down. The researchers speculate that the 30-day trial might not have been long enough for the cream to act on cellulite.
Public release date: 7-Dec-2007
Antibacterial chemical disrupts hormone activities
A new UC Davis study shows that a common antibacterial chemical added to bath soaps can alter hormonal activity in rats and in human cells in the laboratory—and does so by a previously unreported mechanism.
The findings come as an increasing number of studies – of both lab animals and humans – are revealing that some synthetic chemicals in household products can cause health problems by interfering with normal hormone action.
Called endocrine disruptors, or endocrine disrupting substances (EDS), such chemicals have been linked in animal studies to a variety of problems, including cancer, reproductive failure and developmental anomalies
This is the first endocrine study to investigate the hormone effects of the antibacterial compound triclocarban (also known as TCC or 3,4,4′-trichlorocarbanilide), which is widely used in household and personal care products including bar soaps, body washes, cleansing lotions, wipes and detergents. Triclocarban-containing products have been marketed broadly in the United States and Europe for more than 45 years; an estimated 1 million pounds of triclocarban are imported annually for the U.S. market.
The researchers found two key effects: In human cells in the laboratory, triclocarban increased gene expression that is normally regulated by testosterone. And when male rats were fed triclocarban, testosterone-dependent organs such as the prostate gland grew abnormally large.
Also, the authors said their discovery that triclocarban increased hormone effects was new. All previous studies of endocrine disruptors had found that they generally act by blocking or decreasing hormone effects.
“This finding may eventually lead to an explanation for some rises in some previously described reproductive problems that have been difficult to understand,” said one author, Bill Lasley, a UC Davis expert on reproductive toxicology and professor emeritus of veterinary medicine. More analyses of antibacterials and endocrine effects are planned, he said.