CHAPEL HILL – People who use monosodium glutamate, or MSG, as a flavor enhancer
in their food are more likely than people who don’t use it to be overweight or obese even
though they have the same amount of physical activity and total calorie intake, according
to a University of North Carolina at Chapel Hill School of Public Health study published
this month in the journal Obesity.
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Researchers at UNC and in China studied more than 750 Chinese men and women, aged
between 40 and 59, in three rural villages in north and south China. The majority of study
participants prepared their meals at home without commercially processed foods. About
82 percent of the participants used MSG in their food. Those users were divided into
three groups, based on the amount of MSG they used. The third who used the most MSG
were nearly three times more likely to be overweight than non-users
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“Animal studies have indicated for years that MSG might be associated with weight
gain,” said Ka He, M.D., assistant professor of nutrition and epidemiology at the UNC
School of Public Health. “Ours is the first study to show a link between MSG use and
weight in humans.”
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Because MSG is used as a flavor enhancer in many processed foods, studying its
potential effect on humans has been difficult. He and his colleagues chose study
participants living in rural Chinese villages because they used very little commercially
processed food, but many regularly used MSG in food preparation.
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“We found that prevalence of overweight was significantly higher in MSG users
than in non-users,” He said. “We saw this risk even when we controlled for physical
activity, total calorie intake and other possible explanations for the difference in
body mass. The positive associations between MSG intake and overweight were
consistent with data from animal studies.”
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As the percentage of overweight and obese people around the world continues to
increase, He said, finding clues to the cause could be very important.
“The U.S. Food and Drug Administration and other health organizations around
the world have concluded that MSG is safe,” He said, “but the question remains – is
it healthy?”
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Evil: FDA as well as others refuse to investigate the science, exposing the world to an Obesity Epidemic