Data  Rebuttal posted at the end of the arrticle ,to their conflicting hypothesis. Were not going to let them off the hook so easy for this.

  • Currently statins only given to around eight  million high-risk patients
  • But Professor Sir Rory Collins  says healthy people can also benefit
  • Hesaid evidence from 130,000 patients  taking statins shows they’re safe

By Jenny Hope

PUBLISHED:14:23 EST, 28  August 2012| UPDATED:16:32 EST, 28 August 2012

Statins should be given to all over-50s,  regardless of their health history, because they dramatically cut the risk of  heart attacks and strokes in later life, one of the UK’s leading experts has  said.

Currently statins are given only to high-risk  patients, around eight million people, who have high cholesterol or have a risk  of heart disease.

But there is ‘clear evidence’ that healthy  people can also benefit based on their age alone, says Professor Sir Rory  Collins.

Statins are taken each day by eight million adults in the UK but there is 'clear evidence' that healthy people can also benefit, it is claimedStatins are taken each day by eight million adults in  the UK but there is ‘clear evidence’ that healthy people can also benefit, it is  claimed (posed by model)

He led the world’s largest study to  investigate statins in the prevention of cardiovascular disease which proved  that cutting levels of ‘bad’ LDL cholesterol in the blood saved  lives.

The risk of having a major vascular event  such as a heart attack is cut by one-fifth for each 1.0mmol/L (millimoles per  litre) fall in LDL, whether in high or low risk patients.

But current guidelines on their use – and  misguided safety fears about muscle pain and memory loss – are restricting the  range of people who can take them, he said.

‘At 50 you should be considering it and  whether you should be taking them at an earlier age is an open question’ he  said.

‘If you start treatment earlier and continue  for longer the benefits will be much greater, you’re not trying to unfur the  arteries, you’re preventing them from furring in the first place’ he  said.

Prof Collins, who was giving a keynote  lecture at the European Cardiology Congress in Munich, said evidence from  130,000 patients taking statins in trials show they are safe.

Professor Sir Rory Collins says statins should be given to all over-50s, regardless of their health historyProfessor Sir Rory Collins says statins should be given  to all over-50s, regardless of their health history

Yet drug safety watchdogs here and in the US  have insisted on flagging up relatively minor side effects which are putting  patients off the drugs, he said.

These include memory loss, depression, sexual  difficulties and depression, while recent research suggests cataracts and  diabetes may be more common in patients taking statins.

Trial data shows only one significant side  effect, myopathy or muscle pain, which affects one in 10,000 patients, said Prof  Collins.

He said: ‘We need to look properly at the  safety of statins. The reality is that these drugs are remarkably safe, but the  problem is that high risk patients are getting the message that these drugs have  side effects.’

Prof Collins, 57, went to his GP a fortnight  ago to ask about taking statins despite a relatively low cholesterol level, and  was dismayed to learn she could not get high risk patients to take them because  of fears about side effects.

Research earlier this year co-ordinated by  the Clinical Trial Service Unit Oxford University, where Prof Collins is  co-director, reviewed findings from 27 statin trials involving 175,000 people,  some of whom were at low risk of heart problems.

The drugs cut the risk of heart attacks,  strokes and operations to unblock arteries by one third or more.

The benefits were gained no matter what level  of cholesterol patients started out with. Healthier people who were given  statins also had lower overall death rates than those who were given a  placebo.

It concluded the positives greatly exceeded  any side-effects from taking the drugs.

More than eight million adults are already  taking statins, but it is estimated that routine use by the over 50s would lead  to 10,000 fewer heart attacks and strokes a year, including 2,000 fewer deaths  in the UK.

The small cost of the drugs – as low as £16 a  year – would be outweighed by NHS savings due to the reduced number of heart  attacks and strokes.

At present, statins are restricted to those  with at least a 20 per cent risk of having a heart attack or stroke over the  next five years.

But, said Prof Collins, trial data shows very  low risk groups can benefit where individuals have just a five to 10 per cent  chance of heart disease, and even lower.

He said there did not appear to be a  threshold at which the drugs didn’t work and the longer they were taken, the  greater the benefit.

‘We need to review the guidelines and the  current thresholds should go,’ said Prof Collins, who claimed medical tests such  as liver function were also unnecessary.

Professor Peter Weissberg, medical director  of the British Heart Foundation, said: ‘The issue is where do you set the  threshold between low, normal and high risk.

‘The current arbitrary threshold was decided  by cost but now statins are off patent (and much cheaper) it may be appropriate  to see if there are benefits for more people – the threshold is a bit too high,’  he added

Read more: http://www.dailymail.co.uk/health/article-2194892/All-50s-statins-regardless-health-history-says-Oxford-professor.html#ixzz24yfGXdJ1

* No footnoted study is listed to review. We assume they utilized a meta analysis, based upon an unknown statistical model:

Links in Conflict with the Clinical Trial Service Unit Oxford University: ( There are far more, but the intent is to disprove their hypothesis )

http://engineeringevil.com/2012/08/22/cholesterol-lowerings-drugs-may-create-manifestations-of-severe-irritability-included-homicidal-impulses-threats-to-others-road-rage-generation-of-fear-in-family-members-and-damage-to-property/

http://engineeringevil.com/2012/08/20/cholesterol-lowering-drug-linked-to-sleep-disruptions-possibly-promoting-weight-gain-and-insulin-resistance/

http://engineeringevil.com/2012/08/20/relationship-between-statins-and-cognitive-decline-more-complex-than-thought/

http://engineeringevil.com/2012/08/11/cure-all-statins-have-had-no-effect-on-britains-heart-disease-rate-study-claims/

http://engineeringevil.com/2012/07/23/statins-may-increase-risk-of-interstitial-lung-abnormalities-in-smokers/