– Antibiotics being explored for the treatment of cystic fibrosis and muscular dystrophy have the potential to trigger autoimmune disease
– . He identified 17 peptides that hadn’t been characterized before in cells treated with gentamicin and showed that the peptides were presentable to the immune system.
– So even as gentamicin fights the bacteria causing the infection, it also causes normal cells to produce abnormal proteins that are presented to the immune system and have a potential of initiating an autoimmune reaction.
* reported online in Proceedings of the National Academy of Sciences (the week of March 31st)
- Antibiotics may Cause Autoimmunity (medindia.net)
- Can antibiotics cause autoimmunity? (eurekalert.org)
- Can antibiotics cause autoimmunity? (medicalxpress.com)
- Small peptides as potential antibiotics (phys.org)