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New research in the FASEB Journal suggests that a daily intake of resveratrol prevents the ill effects of simulated weightlessness on muscle and bone metabolism

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Public release date: 30-Jun-2011

English: Wine grapes

Bethesda, MD—As strange as it sounds, a new research study published in the FASEB Journal (http://www.fasebj.org), suggests that the “healthy” ingredient in red wine, resveratrol, may prevent the negative effects that spaceflight and sedentary lifestyles have on people. The report describes experiments in rats that simulated the weightlessness of spaceflight, during which the group fed resveratrol did not develop insulin resistance or a loss of bone mineral density, as did those who were not fed resveratrol.

According to Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, “There are overwhelming data showing that the human body needs physical activity, but for some of us, getting that activity isn’t easy. A low gravity environment makes it nearly impossible for astronauts. For the earthbound, barriers to physical activity are equally challenging, whether they be disease, injury, or a desk job. Resveratrol may not be a substitute for exercise, but it could slow deterioration until someone can get moving again.”

Scientists studied rats that underwent simulated weightlessness by hindlimb tail suspension and were given a daily oral load of resveratrol. The control group showed a decrease in soleus muscle mass and strength, the development of insulin resistance, and a loss of bone mineral density and resistance to breakage. The group receiving resveratrol showed none of these complications. Study results further demonstrated some of the underlying mechanisms by which resveratrol acts to prevent the wasting adaptations to disuse-induced mechanical unloading. This study also suggests that resveratrol may be able to prevent the deleterious consequences of sedentary behaviors in humans.

“If resveratrol supplements are not your cup of tea,” Weissmann added, “then there’s good news. You can find it naturally in red wine, making it the toast of the Milky Way.”

About Post Author

Ralph Turchiano

I have a strong affinity for the sciences which led me to create my sites. My compulsion for the past decade has been reviewing literally every peer-reviewed research article. Which can easily be validated by following my posts. To me, science is where the real news is, as it will mold our destiny beyond that of politics or economics. 😉 Please feel free to e-mail: 161803p314159@gmail.com
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