Breaking News

Wound Healing Rapidly Accelerated with Sandalwood Scent ( VIDEO )

0 0

Sandalwood scent facilitates wound healing and skin regeneration

We previously showed that the stimulation of keratinocytes with synthetic sandalwood odorants, often exposed to the skin as ingredients of perfumes, emollients, and cleaning agents, results in a transient increase of the intracellular calcium concentration (Sondersorg et al., 2014). This observation raises the question of whether keratinocytes express physiologically functional ORs that detect odorants such as synthetic sandalwood odorants.
 
Keratinocytes, the major cell type of the epidermal layer, express a variety of different sensory receptors that enable them to react to various environmental stimuli and process information in the skin. Here we report the identification of a novel type of chemoreceptors in human keratinocytes, the olfactory receptors (ORs). We cloned and functionally expressed the cutaneous OR, OR2AT4, and identified Sandalore, a synthetic sandalwood odorant, as an agonist of this receptor.

 
Moreover, the long-term stimulation of keratinocytes with Sandalore positively affected cell proliferation and migration, and regeneration of keratinocyte monolayers in an in vitro wound scratch assay. These findings combined with our studies on human skin organ cultures strongly indicate that the OR 2AT4 is involved in human keratinocyte re-epithelialization during wound-healing processes.

*A Synthetic Sandalwood Odorant Induces Wound-Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4 Journal of Investigative Dermatology (2014) 134, 2823–2832; doi:10.1038/jid.2014.273; published online 7 August 2014

http://clinicalnews.org/2014/07/11/sandalwood-scent-facilitates-wound-healing-and-skin-regeneration/

Please like us on http://www.facebook.com/vitaminandherbstore to stay current or http://www.youtube.com/vhfilm for our archive

About Post Author

Ralph Turchiano

I have a strong affinity for the sciences which led me to create my sites. My compulsion for the past decade has been reviewing literally every peer-reviewed research article. Which can easily be validated by following my posts. To me, science is where the real news is, as it will mold our destiny beyond that of politics or economics. 😉 Please feel free to e-mail: 161803p314159@gmail.com
Happy
Happy
0 %
Sad
Sad
0 %
Excited
Excited
0 %
Sleppy
Sleppy
0 %
Angry
Angry
0 %
Surprise
Surprise
0 %

Average Rating

5 Star
0%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
%d bloggers like this: