Myricitrin may protect against neuronal loss in Parkinson’s disease

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Public Release: 6-Jun-2016


Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, June 6, 2016–A new study has shown that myricitrin, a flavinoid with antioxidant and anti-inflammatory activity that is present inedible plants and fruit, can protect mouse brains from the loss of dopamine-producing neurons caused by neurotoxicity. The reported effects of myricitrin suggest that it could have a role in preventing the neuronal degeneration that occurs in Parkinson’s disease, as described in an article published in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Medicinal Food website until July 6, 2016.

Heung Deok Kim, Kyoung Hoon Jeong, Un Ju Jung and San Ryong Kim, Kyungpook National University (Daegu) and Pukyong National University (Busan), Korea, demonstrated the ability of myricitrin to help maintain two key functions of mouse neurons exposed to a neurotoxic agent: the enzymatic activity of tyrosine hydroxylase and rapamycin complex 1 activation. The authors present their findings in the article entitled “Myricitrin Ameliorates 6-Hydroxydopamine-Induced Dopaminergic Neuronal Loss in the Substantia Nigra of Mouse Brain.”


About the Journal

Journal of Medicinal Food is an authoritative, peer-reviewed, multidisciplinary journal published monthly online with open access options and in print. Led by Editors-in-Chief Sampath Parthasarathy, MBA, PhD, Florida Hospital Chair in Cardiovascular Sciences and Interim Associate Dean, College of Medicine, University of Central Florida, and Yangha Kim, PhD, Ewha Womans University, Seoul, South Korea, the Journal publishes original scientific research on the bioactive substances of functional and medicinal foods, nutraceuticals, herbal substances, and other natural products. The Journal explores the chemistry and biochemistry of these substances, as well as the methods for their extraction and analysis, the use of biomarkers and other methods to assay their biological roles, and the development of bioactive substances for commercial use. Tables of content and a sample issue may be viewed on the Journal of Medicinal Food website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including The Journal of Alternative and Complementary Medicine and Cannabis and Cannabinoid Research. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Categories: Missed - Medical Breakthroughs

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