There is a considerable overlap between vascular and Alzheimer’s disease (AD) risk factors. In addition, incident stroke approximately doubles the risk of developing AD. Oxidative stress is significantly involved in the pathogenesis of AD and suffers a dramatic increase in the setting of acute ischemic stroke, especially in cardioembolic stroke, followed by lacunar stroke, as shown in a previous study. Dampening this oxidative burst could delay the onset of subsequent dementia in stroke survivors.
Source: Antioxidant treatment in acute ischemic stroke may delay the onset of Alzheimer’s dementia