Probiotic Strain LA1, a major leap forward for Intestinal disorders

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Probiotic Strain LA1, a major leap forward for Intestinal disorders

“Our data indicate that LA1 is able to prevent colonic inflammation formation and promote colitis healing,” said lead investigator Thomas Ma, MD, PhD, Penn State College of Medicine, Hershey Medical Center, Hershey, PA, USA. “The implications of the present findings are that this bacterial strain can be used in a wide variety of intestinal permeability disorders, including IBD, coeliac disease, alcoholic liver disease, non-alcoholic fatty liver disease, and necrotizing enterocolitis, to treat inflammation associated with the leaky gut.”

#LA1 #probiotic #IBD

Rana Al-Sadi et al, Lactobacillus acidophilus Induces a Strain-specific and Toll-Like Receptor 2–Dependent Enhancement of Intestinal Epithelial Tight Junction Barrier and Protection Against Intestinal Inflammation, The American Journal of Pathology (2021). DOI: 10.1016/j.ajpath.2021.02.003

Leaky gut, intestinal permeability disorders, IBD, coeliac disease, alcoholic liver disease, non-alcoholic fatty liver disease, necrotizing enterocolitis, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus rhamnosus, LA1, pithelial, tight junction barrier, colonic inflammation, intestinal barrier , Toll-Like Receptor 2



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