What The Study Did: Researchers used a large data resource of U.S. COVID-19 cases and control patients who tested negative from multiple health systems across the country to evaluate COVID-19 severity and risk factors over time and assess the use of machine learning to predict clinical severity.

Authors: Tellen D. Bennett, M.D., of the University of Colorado School of Medicine in Aurora, and Christopher G. Chute, M.D., of Johns Hopkins University in Baltimore, are corresponding authors.

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(doi:10.1001/jamanetworkopen.2021.16901)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: The full study and commentary are linked to this news release.

 

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Source: Clinical characterization, prediction of severity of SARS-CoV-2 infection among US adults