New University of Kentucky study offers insight on how resistance training burns fat

Read Time:2 Minute, 33 Second

LEXINGTON, Ky. (Aug. 9, 2021) — Findings from a new University of Kentucky College of Medicine and College of Health Sciences study add to growing evidence that resistance exercise has unique benefits for fat loss.

The Department of Physiology and Center for Muscle Biology study published in the FASEB Journal found that resistance-like exercise regulates fat cell metabolism at a molecular level.

The study results in mice and humans show that in response to mechanical loading, muscle cells release particles called extracellular vesicles that give fat cells instructions to enter fat-burning mode.

Extracellular vesicles were initially understood as a way for cells to selectively eliminate proteins, lipids and RNA. Recently, scientists discovered that they also play a role in intercellular communication.

The study adds a new dimension to how skeletal muscle communicates with other tissues by using extracellular vesicles, says John McCarthy, Ph.D., study author and associate professor in the UK Department of Physiology.

“To our knowledge, this is the first demonstration of how weight training initiates metabolic adaptations in fat tissue, which is crucial for determining whole-body metabolic outcomes,” McCarthy said. “The ability of resistance exercise-induced extracellular vesicles to improve fat metabolism has significant clinical implications.”

McCarthy’s research team was led by post-doc Ivan Vechetti, now at the University of Nebraska, in collaboration with the Center for Muscle Biology, directed by Joseph Hamburg Endowed Professor Charlotte Peterson, Ph.D.

The study was recently featured in The New York Times.

Research reported in this publication was supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under Award Number R01DK119619. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. 

The University of Kentucky is increasingly the first choice for students, faculty and staff to pursue their passions and their professional goals. In the last two years, Forbes has named UK among the best employers for diversity, and INSIGHT into Diversity recognized us as a Diversity Champion four years running. UK is ranked among the top 30 campuses in the nation for LGBTQ* inclusion and safety. UK has been judged a “Great College to Work for” three years in a row, and UK is among only 22 universities in the country on Forbes’ list of “America’s Best Employers.”  We are ranked among the top 10 percent of public institutions for research expenditures — a tangible symbol of our breadth and depth as a university focused on discovery that changes lives and communities. And our patients know and appreciate the fact that UK HealthCare has been named the state’s top hospital for five straight years. Accolades and honors are great. But they are more important for what they represent: the idea that creating a community of belonging and commitment to excellence is how we honor our mission to be not simply the University of Kentucky, but the University for Kentucky.

Source: New University of Kentucky study offers insight on how resistance training burns fat



Categories: All Posts

Average Rating

5 Star
0%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
%d bloggers like this: