A product of a freshwater single-celled green algae called Euglena gracilis may enhance skin regeneration to speed up wound healing, according to new research published in Advanced Materials Interfaces.
Investigators developed a system based on microvesicles that bud from the cell surface of Euglena gracilis and contain β-glucan, a carbohydrate with immunoregulatory activity, regeneration ability, and antioxidant properties.
In laboratory experiments, these microvesicles promoted the proliferation and migration of skin cells, increasing both collagen synthesis and the expression of proliferation-associated proteins. A wound healing test also generated promising results.
“This technique is expected to be applied to other cells, thereby enabling the design of new types of extracellular vesicles that are applicable for skin treatments and care in the pharmaceutical and cosmetic industries,” the authors wrote.
URL upon publication: https://onlinelibrary.wiley.com/doi/10.1002/admi.202202255
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About the Journal
Advanced Materials Interfaces publishes applied, top-level research on functional interfaces and surfaces and their specific applications, driving forward our understanding of interfacial processes. Considering that interfaces between solids, liquids, and gases play an essential role in virtually all materials and devices, the journal’s scope encourages an interdisciplinary blend of physics, chemistry, materials science, and life sciences
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Advanced Materials Interfaces
Nonanimal Euglena gracilis-Derived Extracellular Vesicles Enhance Skin-Regenerative Wound Healing
ARTICLE PUBLICATION DATE
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