Implications for the Future- In essence, this groundbreaking research indicates that by encouraging the recycling of mitochondria using Urolithin A, it is possible to reverse the aging process within the hematopoietic and immune systems. These findings hold immense promise for the development of interventions targeted at addressing age-related health conditions in older individuals and pave the way for envisioning clinical trials.
#urolithinA #ellagic #ellagitannins
Girotra, M., Chiang, Y., Charmoy, M., Ginefra, P., Hope, H. C., Bataclan, C., Yu, Y., Schyrr, F., Franco, F., Geiger, H., Cherix, S., Ho, P., Naveiras, O., Auwerx, J., Held, W., & Vannini, N. (2023). Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems. Nature Aging, 1-10. https://doi.org/10.1038/s43587-023-00473-3
An, L., Lu, Q., Wang, K., & Wang, Y. (2023). Urolithins: A Prospective Alternative against Brain Aging. Nutrients, 15(18), 3884. https://doi.org/10.3390/nu15183884
Urolithin A, ellagic, ellagitannins, stem cells, immune system, brain aging, hematopoietic, blood brain barrier, aging, age-associated decline, HSC, URO, UroA