Month: August 2009

Off-label use: Oft not evidence base

Public release date: 21-Aug-2009  – in 2006 indicated that approximately 21% of drug uses in the United States occur for off-label purposes, – with 73% of those cases lacking scientific evidence of the drug’s effectiveness   Physicians lack knowledge of off-label drug use and FDA approval status CHICAGO – In a recent national survey, a…

Research shows why low vitamin D raises heart disease risks in diabetics

Public release date: 25-Aug-2009   – They have found that diabetics deficient in vitamin D can’t process cholesterol normally, so it builds up in their blood vessels By Jim Dryden Aug. 21, 2009 — Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers…

Hormone therapy for prostate cancer patients with heart conditions linked to increased death risk – Kills twice as fast

Public release date: 25-Aug-2009 – , neoadjuvant HT use was associated with nearly twice the risk of all-cause mortality (26.3 percent vs. 11.2 percent). Men with coronary artery disease-induced congestive heart failure or heart attack who receive hormone therapy before or along with radiation therapy for treatment of prostate cancer have an associated increased risk…

More obesity blues

Public release date: 25-Aug-2009 – They found that obese people had 8 percent less brain tissue than people with normal weight, while overweight people had 4 percent less tissue. UCLA and Pittsburgh researchers report that obese people are at greater risk for developing Alzheimer’s Obesity is on a rampage, with the World Health Organization pegging…

Unlocking the body’s defenses against cancer

Public release date: 25-Aug-2009 – ‘kinase inhibitors’ opened up communication channels on the surface of cells that enabled healthy cells to ‘talk’ to the cancer cells. – When we added the chemicals to a mixture of healthy and cancerous cells in a flask the diseased cells stopped multiplying and began acting like normal cells again,”…

Discovery of natural odors could help develop mosquito repellents

Public release date: 26-Aug-2009   – “CO2 emitted in human breath is the main attractant for the Culex mosquito to find people, aiding the transmission of these deadly diseases,”   Applications of research by UC Riverside entomologists include prevention of West Nile virus and other mosquito-borne diseases RIVERSIDE, Calif. – Entomologists at the University of…

Heat forms potentially harmful substance in high-fructose corn syrup

Public release date: 26-Aug-2009 – Levels jumped dramatically at about 120 degrees Fahrenheit. – The substance, hydroxymethylfurfural (HMF), forms mainly from heating fructose. – studies have linked HMF to DNA damage in humans. In addition, HMF breaks down in the body to other substances potentially more harmful than HMF.   Researchers have established the conditions…

Nuisance or nutrient? Kudzu shows promise as a dietary supplement

Public release date: 26-Aug-2009 –  After two months of taking the extract, the rats had lower cholesterol, blood pressure, blood sugar, and insulin levels that a control group not given the extract. Kudzu, the nuisance vine that has overgrown almost 10 million acres in the southeastern United States, may sprout into a dietary supplement. Scientists…

People vary widely in ability to eliminate arsenic from the body

Public release date: 26-Aug-2009   –  They found that ability to eliminate arsenic from the body varied greatly, with some participants excreting up to 95 percent of the ingested arsenic but others eliminating as little as four percent. Large variations exist in peoples’ ability to eliminate arsenic from the body, according to a new study…

Immune defect is key to skin aging

Public release date: 27-Aug-2009 – “We also, obviously, would like to know if it is possible to reverse the skin defect in older people. We’ve done some experiments that show that, at least in the test tube, it is possible to make older skin express the missing signals that attract T cells. This indicates that,…

Natural compounds, chemotherapeutic drugs may become partners in cancer therapy

Public release date: 27-Aug-2009  – chlorophyllin kills cancer cells by blocking the same phase of cellular division that hydroxyurea does, but by a different mechanism     CORVALLIS, Ore. – Research in the Linus Pauling Institute at Oregon State University suggests that some natural food compounds, which previously have been studied for their ability to…

Daily aspirin does more harm than good: study

September 1, 2009 – there was no difference in the number of heart attacks, strokes and other cardiovascular events suffered, major bleeding occurred in two percent of the aspirin group compared to just 1.2 percent of the placebo group.   LONDON (AFP) – Healthy people taking a daily dose of aspirin to prevent heart attacks…

The popular insect repellent deet is a neurotoxin

Public release date: 4-Aug-2009 – “We’ve found that deet is not simply a behavior-modifying chemical but also inhibits the activity of a key central nervous system enzyme, acetycholinesterase, in both insects and mammals”. The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in…

A synthetic derivative of the kudzu vine can reduce drinking and prevent relapse

Public release date: 11-Aug-2009   •Kudzu extracts have been used in Chinese folk medicine to treat alcoholism for about 1,000 years. •Daidzin is an anti-drinking substance in kudzu. •A synthetic form of daidzin, called CVT-10216, can successfully reduce drinking and prevent relapse in preclinical rodent models. Kudzu and its extracts and flowers have been used…

Carnitine supplements reverse glucose intolerance in animals

Public release date: 12-Aug-2009     DURHAM, N.C. – Supplementing obese rats with the nutrient carnitine helps the animals to clear the extra sugar in their blood, something they had trouble doing on their own, researchers at Duke University Medical Center report. A team led by Deborah Muoio (Moo-ee-oo), Ph.D., of the Duke Sarah W.…