The results showed that:

• Aspirin use was associated with an 11% lower risk of cardiovascular events.
• Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death.
• Aspirin use was associated with a 43% of major bleeding events, compared to those who did not take it.
• Approximately one in 200 people treated with aspirin would have a major bleed.
• No effect was seen with aspirin on new cancer diagnoses or deaths.

A new study published today in the Journal of the American Medical Association (JAMA) has found that taking aspirin on a regular basis to prevent heart attacks and strokes, can lead to an increase risk of almost 50 percent in major bleeding episodes.

Source: Frequent use of aspirin can lead to increased bleeding