Research shows that controlling inflammation may be key to helping the brain develop the flexibility to respond to antidepressant drugs, potentially opening the way for treatment for many millions of people who do not respond to the drugs. This is experimental work on mice, and has not yet been confirmed in humans. It is presented together for the first time at the ECNP Congress in Copenhagen, after a series of publications in peer-reviewed journals.
Source: Why don’t the drugs work? Controlling inflammation can make antidepressants more effective