The data suggest a novel approach to treatment of PTSD, which involves combining two natural products that modulate the epigenome. Importantly, epigenetic treatments reverse the underlying causes of the disorder on DNA and thus serve as a “cure” rather than temporary relief of symptoms. “Since these nutritional supplements are relatively nontoxic, they offer hope for a nontoxic treatment of PTSD that reverses the underly
Warhaftig, G., Zifman, N., Sokolik, C.M. et al. Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy. Mol Psychiatry (2021). https://doi.org/10.1038/s41380-021-01178-y
Same, vitamin a, retinoic acid, , epigenetic, methyl donor, epigenetic DNA methylation marks, S-adenosylmethionine, cause, DNMT3a, Retinoic Acid Receptor, RAR, genomic , nucleus accumbens, Post-traumatic stress disorder