Narrator Ralph Rurchiano

Prevent Recurrent Heart Attacks, Targeted Vitamin D Dosing, Acute Coronary Syndrome Treatment, TARGET-D Trial Results 2025, Vitamin D Levels for Heart Health, Reducing MACE Risk, Intermountain Health Study.
In this episode, we dive into the groundbreaking TARGET-D trial (presented at AHA 2025) that shows how “treating to target”—adjusting Vitamin D dosage to reach specific blood levels—may significantly reduce the risk of recurrent heart attacks. While the overall cardiovascular risk (MACE) didn’t change statistically in the broad group, the study found a significant reduction in repeat heart attacks (Myocardial Infarction) for those in the treatment group. Learn the difference between “Intention to Treat” and “Per Protocol” analysis and what this means for secondary heart prevention.

Source: May HT, Le VT, Anderson JL, et al. A Randomized Clinical Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovascular-Related Events Among Acute Coronary Syndrome Patients: The TARGET-D Trial. Abstract presented at: American Heart Association Scientific Sessions 2025; November 9, 2025; New Orleans, LA.

Disclaimers:

  • This information is for educational purposes only and should not be interpreted as medical advice.
  • The study discussed was conducted on Acute Coronary Syndrome patients (survivors of heart attack or unstable angina). These findings may not apply to the general healthy population.
  • Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan.
  • This channel does not provide medical advice.

#VitaminD #HeartAttack #TARGETD #Cardiology #MedicalResearch

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