My Personal Biomedical Research Feed – Ralph Turchiano, CEO Alchepharma
This 2026 study highlights d-Limonene (LIM) as a potent dietary bioactive for gout and hyperuricemia treatment. It suppresses the NLRP3-IL-1β inflammatory pathway and enhances antioxidant levels, offering nephroprotective and hepatoprotective…
This study analyzed the effects of D-Allulose and oral semaglutide on diet-induced obese mice. Both compounds reduced food intake and body weight initially by activating specific neurons. Notably, D-Allulose inhibited…
A 2025 JCI Insight study highlights that rosemary extract, specifically carnosic acid, significantly enhances scarless wound healing by activating the TRPA1 nociceptor in sensory neurons. In mouse models, daily application…
A 2025 study in Science Advances reveals that NAD+ may combat Alzheimer's disease by correcting dysfunctional gene splicing errors linked to aging and AD. It regulates the EVA1C protein, crucial…
A study published in Nutrients examined the protective effects of Lepidium meyenii Walpers (Maca) on radiation-induced salivary gland damage in mice. Mice treated with Maca extract showed reduced saliva secretion…
https://youtu.be/DIvNWO4tbok?si=fyAIDrRsuRXbgQAE A recent study in the journal GeroScience investigated how age-related declines in cellular energy, specifically the molecule Guanosine triphosphate (GTP), affect waste clearance in brain cells. Using hippocampal neurons…
A study in Advanced Healthcare Materials reveals a new technique for regenerating tooth enamel using keratin-based films. These films self-assemble into scaffolds that promote the growth of apatite nanocrystals, repairing…
A study in Nature highlights a significant connection between lithium levels in the brain and Alzheimer's disease. Researchers found lithium reduced in those with mild cognitive impairment and AD. Mouse…
A recent study on mice examined the effects of lactoferrin and creatine on age-related muscle loss, or sarcopenia. Mice treated with both supplements showed significant improvements in lean body mass,…
This research investigated Keyfobell Powder (KFB), a blend of herbal extracts, for its ability to enhance longitudinal bone growth by upregulating IGF-1, similar to somatropin. KFB significantly increased IGF-1 levels…
The study investigated elderberry extract's impact on testosterone levels in rats with testosterone deficiency syndrome (TDS). Results showed significant increases in total testosterone: 113.4% in the low-dose, 219.3% in the…
The groundbreaking UCLA Health study highlights the potential of Manuka honey as a natural alternative for breast cancer treatment. The research shows significant reduction in tumor growth in mice with…
Irvine, Calif., Aug. 20, 2024 — A team of researchers led by the University of California, Irvine has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of…
FINDINGS A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment— particularly…
COLUMBUS, Ohio – Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring, according to a new study led by The Ohio…
UNIVERSITY PARK, Pa. — Early life exposure to ‘forever chemicals’ in the environment permanently disrupts the gut microbiome in mice, contributing to the development of metabolic disease in later life,…
Early-stage trials in Alzheimer’s disease patients and studies in mouse models of the disease have suggested positive impacts on pathology and symptoms from exposure to light and sound presented at the “gamma”…
Parkinson’s disease is a neurodegenerative disease caused by the loss of neurons that produce dopamine, a neurotransmitter involved in motor control and cognitive function. As the global population ages, the…
A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress. The…
https://youtu.be/WSqOZfBr2lg?si=UdTfvjuXUdd6B-_C Breakthrough! Natural Olive Extract for Weight Loss? Ep. 1198 JUL 2024 Mice got slimmer and healthier thanks to a compound in olives! A new study found elenolic acid, a…
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