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In head-to-head trials of two drugs, the one deemed better appears to depend largely on who is funding the study, according to an analysis of nearly 200 statin-drug comparisons carried out between 1999 and 2005. UCSF researchers examined 192 published results of trials comparing one cholesterol-lowering statin drug to another, or to a non-statin drug. Their findings found that two links stood out. If the reported results favored the test drug, the trial was about 20 times more likely to be funded by the maker of the statin rather than the comparison drug company. Even more striking, they say, if […]
Public release date: 8-Jan-2007 Additional research presented at the 19th World Diabetes Congress Meeting supports the efficacy and safety of chromium picolinate in diabetes management The 30-day study examined thirty-six overweight or obese poorly controlled patients with type 2 diabetes taking Diachrome who were already receiving oral anti-diabetic drug(s). The results also showed a significantly greater reduction in the total area under the curve for glucose (AUCg) during the oral glucose tolerance test (OGTT) for the treatment group (mean change -9.7%) compared with the placebo group (mean change +5.1%). Mean fructosamine levels, a measure of the average blood […]
CHICAGO, June 4, 2007 — Women on tamoxifen therapy who reported having hot flashes were less likely to develop recurrent breast cancer than those who did not report hot flashes, according to a study from the Moores Cancer Center at the University of California, San Diego (UCSD). Moreover, hot flashes were a stronger predictor of outcome than age, hormone receptor status or even how advanced the breast cancer was at diagnosis Cancer recurrence among women who reported hot flashes was about 12.9 percent, compared with 21 percent for women not reporting hot flashes. These data were consistent across all years […]
North Central Cancer Treatment Group reports on pilot ginseng study CHICAGO — North Central Cancer Treatment Group (NCCTG) researchers, based at Mayo Clinic in Rochester, Minn., have generated preliminary data suggesting that a form of American ginseng provides greater improvements in fatigue and vitality in patients who receive the highest doses tested, compared to lower doses or no treatment. The results of their scientifically rigorous pilot study, the first to evaluate the Wisconsin species of American ginseng as a possible therapy for cancer-related fatigue, are being presented June 3 at the annual meeting of the American Society of Clinical Oncology […]
Public release date: 2-Jun-2007 DURHAM, N.C. — Flaxseed, an edible seed that is rich in omega 3-fatty acids and fiber-related compounds known as lignans, is effective in halting prostate tumor growth, according to a study led by Duke University Medical Center researchers. The seed, which is similar to a sesame seed, may be able to interrupt the chain of events that leads cells to divide irregularly and become cancerous. “Our previous studies in animals and in humans had shown a correlation between flaxseed supplementation and slowed tumor growth, but the participants in those studies had taken flaxseed in conjunction with […]
Folic acid supplementation may reduce the risk of stroke by 18 percent or more, but it’s not clear whether it boosts outcomes for other cardiovascular conditions, researchers say. For the new research, a U.S. team reviewed eight studies of folic acid supplementation, which lowers concentrations of homocysteine in the blood. High homocysteine levels are believed to increase the risk of stroke, cardiovascular disease, and deep vein thrombosis. Professor Xiaobin Wang, of Northwestern University Feinberg School of Medicine in Chicago, and colleagues found that folic acid supplementation reduced the risk of stroke by an average of 18 percent. Even […]
Consumer ads for a class of antidepressants called SSRIs often claim that depression is due to a chemical imbalance in the brain, and that SSRIs correct this imbalance, but these claims are not supported by scientific evidence, say researchers in PLoS Medicine. Although scientists in the 1960s suggested that depression may be linked to low brain levels of the chemical serotonin (the so-called “serotonin hypothesis”), contemporary research has failed to confirm the hypothesis, they say. The researchers–Jeffrey Lacasse, a doctoral candidate at Florida State University and Dr. Jonathan Leo, a neuroanatomy professor at Lake Erie College of Osteopathic Medicine–studied US […]
A COMMON microbe could help to trigger Alzheimer’s disease, say researchers in the US. If true, their controversial claim could turn the multimillion-dollar field of Alzheimer’s research on its head and force a rethink on how to prevent the disease. The microbe in question is Chlamydia pneumoniae, which is spread by coughs and sneezes. By the age of 20, half the population have been infected with C. pneumoniae, and the likelihood of being infected increases with age. The bacterium has already been accused of triggering atherosclerosis-blocked arteries that can lead to heart attacks (“Can you catch a heart attack?”, […]
Public release date: 30-Jul-2009 COLUMBUS, Ohio – A virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute. The researchers examined tissue samples from 58 people with squamous cell carcinoma (SCC), a highly curable form of skin cancer that is expected to affect more than 200,000 Americans this year. They identified the Merkel cell polyomavirus in more than a third of the […]
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