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A major randomized controlled trial, the COSMOS study, previously established a stunning statistic: older adults taking daily cocoa extract experienced a 27% reduction in cardiovascular disease death. However, the biological reason why remained unclear—until now. A new analysis published in Age and Ageing (Sept 2025) examined the bloodwork of 598 participants over two years. The researchers discovered that the cocoa extract (containing 500mg of flavanols) significantly reduced “inflammaging”—specifically lowering high-sensitivity C-reactive protein (hsCRP) by 8.4%. This reduction in chronic inflammation offers the “missing link” that explains the mechanism behind the massive 27% drop in cardiovascular mortality. #CardiovascularHealth #CocoaExtract #27Percent #Inflammaging […]
Description: Can a natural herbal supplement actually improve game speed and recovery? A new 2025 study on professional basketball players suggests the answer might be yes.In this video, we break down research published in the journal Nutrients that tested the effects of Rhodiola rosea on 48 professional male basketball players over a 28-day period. We analyze the data on simulated game performance, VO2max, and fatigue levels to see if this “golden root” is the real deal for athletes.🔍 In This Video We Cover: #RhodiolaRosea #BasketballScience #AthleteRecovery #VO2Max #sportsnutrition Rhodiola rosea benefits, basketball performance training, herbal supplements for athletes, increase VO2max […]
Prevent Recurrent Heart Attacks, Targeted Vitamin D Dosing, Acute Coronary Syndrome Treatment, TARGET-D Trial Results 2025, Vitamin D Levels for Heart Health, Reducing MACE Risk, Intermountain Health Study.In this episode, we dive into the groundbreaking TARGET-D trial (presented at AHA 2025) that shows how “treating to target”—adjusting Vitamin D dosage to reach specific blood levels—may significantly reduce the risk of recurrent heart attacks. While the overall cardiovascular risk (MACE) didn’t change statistically in the broad group, the study found a significant reduction in repeat heart attacks (Myocardial Infarction) for those in the treatment group. Learn the difference between “Intention to […]
A groundbreaking 2025 study published in Science Advances reveals a specific mechanism by which NAD+ may fight Alzheimer’s disease (AD). Researchers discovered that aging and AD are linked to “dysfunctional alternative splicing events” (ASEs)—essentially errors in how gene instructions are assembled. The study found that augmenting NAD+ levels corrects these splicing errors. Specifically, NAD+ regulates a protein called EVA1C, which is critical for neuronal development but found at reduced levels in the hippocampus of AD patients. In mouse models carrying pathological Tau, NAD+ treatment improved memory retention. However, when the researchers genetically blocked EVA1C, the memory-boosting benefits of NAD+ completely […]
Collectively, the results of this study position A. conyzoides as a promising, safe, and well-tolerated adjunct or alternative to current pharmacological approaches. Further investigations of longer duration and larger sample sizes, incorporating imaging measures, are warranted to confirm efficacy.A plant commonly known as “billygoat weed” (Ageratum conyzoides) has a long tradition of use in ethnomedicine for a wide range of conditions, including rheumatism, inflammatory pain, fever, and headaches.Building on this history, a recent 12-week, double-blind, randomized, placebo-controlled study investigated its effect on osteoarthritis (OA) symptoms in ageing adults. The study included 70 adults aged 45 and older with clinically diagnosed […]
A recent study published in Nutrients investigated the effects of dark chocolate (DC) on anaerobic sprint performance. The study involved twenty healthy participants who completed a randomized, single-blinded experiment.Participants completed two trials: one after consuming DC milk and another after consuming an iso-caloric white chocolate (WC) milk, which served as a flavonoid-free control. In each trial, they performed a Running Anaerobic Sprint Test (RAST), which consisted of two sets of six 35-meter sprints.The results showed that DC supplementation significantly improved performance in the second set of sprints: #DarkChocolate #AnaerobicPerformance #SprintTest #ExerciseScience #SportsNutrition Dark chocolate, anaerobic performance, RAST, running anaerobic sprint […]
A 2025 systematic review published in the journal Nutrients analyzed the role of folate supplementation in managing peripheral neuropathy (PN). The review synthesized data from 12 studies, which included a total of 3015 patients. The findings demonstrated “promising symptomatic benefits”. This included pain reductions reaching 3 points , symptom resolution rates as high as 87.5% , and improvements in Neuropathy Total Symptom Score (NTSS-6) scores ranging from 0.9 to 1.5 points.Beyond symptoms, the review also highlighted objective structural improvements, such as increases in epidermal nerve fiber density (ENFD) that reached 97% in one case. Furthermore, folate supplementation was found to […]
A study in the journal Nutrients explored the effects of Lepidium meyenii Walpers (LMW), also known as Maca, on salivary gland damage caused by radiation in mice. Researchers found that mice treated with an LMW extract (LMWE) showed significant improvements compared to an untreated radiation-injury group. Specifically, LMWE treatment reduced the saliva secretion lag time from about 198 seconds in the injured group to as low as 159 seconds. Furthermore, the higher dose of LMWE increased salivary amylase activity by over 20% and helped restore the weight of the salivary glands. The study also identified two potentially new active compounds […]
A recent 8-week, randomized, double-blind, placebo-controlled pilot study explored the effects of the probiotic strain Weizmannia coagulans BC99 on symptoms of anxiety and depression. The trial involved 79 participants who received either 3 grams of the BC99 probiotic, containing 5 billion CFUs, or a placebo daily. While both groups saw improvements, the BC99 group experienced a greater reduction in depression and anxiety scores (HAMD and HAMA scales) compared to the placebo group, though this difference was not statistically significant.More significantly, the study found that BC99 supplementation led to several key biological changes. It helped regulate inflammatory cytokines, notably increasing the […]
The present study demonstrates that green tea extract and ginger supplementation, individually and in combination, enhanced endurance performance, metabolic efficiency, and thermal perception in recreationally active males under normothermic and cold conditions. Green tea alone increased time to exhaustion and reduced respiratory exchange ratio in normothermic conditions, indicating improved fat oxidation and endurance capacity. In cold conditions, the combination of green tea and ginger enhanced time to exhaustion, lowered the respiratory exchange ratio, improved thermal sensation, and reduced muscle soreness. These effects are most pronounced in cold environments, where the combined supplementation mitigated the heightened physiological demands of cold exposure […]
A major scientific review looked at the best available evidence on apple cider vinegar (ACV) and its effects on body weight. Researchers combined the results from 9 different studies that included adults who were overweight, obese, or had type 2 diabetes.Here’s what they found: #AppleCiderVinegar #WeightLoss #BodyComposition #MetaAnalysis #ObesityResearch Source Article Citation:Castagna, A.; Ferro, Y.; Noto, F.R.; et al. Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients 2025, 17, 3000. DOI: https://doi.org/10.3390/nu17183000Apple cider vinegar, ACV, acetic acid, weight management, body composition, […]
A recent randomized, double-blind, placebo-controlled study published in the journal Nutrients investigated the effects of Cistanche deserticola (CD) supplementation on muscle strength and recovery. The eight-week trial involved 48 male participants, who were divided into resistance-trained and untrained groups. Participants in the intervention group received 5 g of CD extract twice daily, for a total of 10 g per day, while following a standardized resistance training program three times per week.Among untrained individuals, the CD group showed significantly greater improvements in 1RM bench press, 1RM squat, maximal voluntary isometric contraction (MVIC), and repetitions to failure (RTF) compared to the placebo […]
A new study in the journal Food Quality and Preference investigated if increasing the spiciness of a meal could influence eating behaviors and reduce how much food people consume. In a series of experiments, researchers had adults eat either a mild or a spicy version of beef chili or chicken tikka masala in a lab setting. The results were significant: when participants ate the spicy beef chili, they consumed 11% less food (about 46 grams) and ate 11% more slowly compared to when they ate the mild version. A similar outcome was observed with a reformulated chicken tikka masala, where […]
A recent crossover randomized controlled trial published in the journal Nutrients investigated the effects of paprika xanthophylls (PX) on endurance and cognitive function in 21 healthy college students. Participants took a supplement containing 9 mg of PX daily for one month and were compared against a control condition (no intake). The study found significant improvements in physical endurance for the PX group, including higher exercise efficiency during both incremental (p=0.004) and constant load tests (p=0.030). Heart rate was also significantly lower during both the incremental test (p=0.032) and the constant load test (p=0.020). While there were no significant differences between […]
A recent study in the journal GeroScience investigated how age-related declines in cellular energy, specifically the molecule Guanosine triphosphate (GTP), affect waste clearance in brain cells. Using hippocampal neurons from an Alzheimer’s disease (AD) mouse model, researchers found a significant, age-dependent reduction in free GTP levels, which was accelerated in the AD model neurons. This energy deficit was shown to impair critical cellular processes like endocytosis and autophagy, leading to the accumulation of toxic amyloid-beta (Aß) aggregates and increased protein oxidation. Remarkably, the researchers then treated aged neurons for 24 hours with a combination of nicotinamide (a precursor to the […]
A recent study in Advanced Healthcare Materials reports a novel method for regenerating tooth enamel using water-based films made from keratin, a protein abundant in sources like wool. Researchers found that these keratin films can self-assemble into organized scaffolds that guide the growth of aligned apatite nanocrystals, mimicking natural enamel formation. When applied to artificially created early enamel lesions (white spot lesions), the keratin-based system was able to repair the damage, restoring both the tooth’s optical appearance and its mechanical properties. Notably, the mechanical recovery was significant; nanoindentation tests showed the elastic modulus of damaged enamel increased from ~5 GPa […]
A study in the journal Nature has uncovered a significant link between the brain’s natural lithium levels and Alzheimer’s disease (AD). After analyzing 27 different metals in post-mortem human brain tissue, researchers found lithium was the only one significantly reduced in individuals with both mild cognitive impairment (MCI) and AD. The research also showed that amyloid-β plaques, a key marker of AD, trap lithium, which further lowers its availability for use by brain cells.To confirm this link, scientists conducted experiments on mouse models. They found that reducing the brain’s lithium levels by roughly 50% caused an acceleration of AD-like pathology, […]
A recent network meta-analysis published in the journal Nutrients systematically compared the effectiveness of seven common nutritional supplements for treating knee osteoarthritis (KOA). The analysis included 39 randomized controlled trials (RCTs) with a total of 4,599 patients. Researchers evaluated the impact of eggshell membrane, vitamin D, Boswellia, curcumin, ginger, krill oil, and collagen against a placebo for improving pain, stiffness, and function. The results showed that compared to a placebo, Boswellia provided statistically significant improvements across all measures, including WOMAC pain (mean difference [MD] = -10.58), stiffness (MD = -9.47), function (MD = -14.00), and VAS pain (MD = -17.26). […]
A recent study published in Frontiers in Psychology surveyed 1,082 participants to investigate how food influences sleep and dreams, exploring direct food effects, physiological symptoms (food distress), and altered sleep quality. The study found that 40.2% of participants reported food affecting their sleep, with 24.7% claiming it worsened sleep and 20.1% reporting improvement. Furthermore, 5.5% of participants experienced food-dependent dreaming. The perceived effect of food on dreams was linked to higher nightmare recall and Nightmare Disorder Index scores. Desserts/sweets (31%) and dairy (22%) were most frequently blamed for disturbing dream changes. The study also revealed associations between perceived food-dependent dreaming […]
A recent randomized, placebo-controlled, crossover trial investigated the link between high-dose oral thiamine supplementation and chronic fatigue in 40 patients with quiescent inflammatory bowel disease (qIBD). The study found that while high-dose thiamine (600-1800 mg/day for 4 weeks) significantly reduced fatigue, it did not alter the overall gut microbiota composition or short-chain fatty acid (SCFA) concentrations.Instead, the study revealed a significant correlation: patients with higher baseline levels of the gut bacteria Faecalibacterium prausnitzii and Roseburia hominis were more likely to respond positively to thiamine treatment. Specifically, Faecalibacterium prausnitzii was more abundant in thiamine responders both before (P=.019) and after (P=.038) […]
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