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Alkaline Water and L-Glutamine: Impact on Testosterone and Recovery EP. 1176 FEB 2024

In a scientific knockout, a study found that athletes who consumed both alkaline water and L-glutamine before exercise experienced a significant boost in salivary α-amylase activity, indicating enhanced immunity. They also saw a rise in testosterone levels, potentially indicating faster muscle recovery. While the mechanisms require further investigation, this suggests a possible synergistic effect between the two substances. Although research focuses on athletes, it raises intriguing possibilities for anyone seeking to optimize recovery and potentially improve immune function. Remember, science is always evolving, offering new tools to support your well-being. #SportRecovery #AlkalineWater #lglutamine Lu, T., He, C., Suzuki, K., Lu, […]
Read more » Alkaline Water and L-Glutamine: Impact on Testosterone and Recovery EP. 1176 FEB 2024

Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases—Focus on Epigenetic Mechanisms

AbstractThe most common malignant gynecologic diseases are cervical, uterine, ovarian, vaginal, and vulvar cancer. Among them, ovarian cancer causes more deaths than any other cancer of the female reproductive system. A great number of women suffer from endometriosis, uterine fibroids (UFs), adenomyosis, dysmenorrhea, and polycystic ovary syndrome (PCOS), which are widespread benign health problems causing troublesome and painful symptoms and significantly impairing the quality of life of affected women, and they are some of the main causes of infertility. In addition to the available surgical and pharmacological options, the effects of supporting standard treatment with naturally occurring compounds, mainly polyphenols, […]
Read more » Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases—Focus on Epigenetic Mechanisms

Study shows impact of antidepressants on fetal brain development during pregnancy

A new study published in Nature Communications provides direct evidence that antidepressant use during pregnancy can impact a child’s brain development and contribute to the risk of mental health disorders later in life. The study, led by researchers at the University of Colorado Anschutz Medical Campus, focused on the effect of fluoxetine, commonly used in medications such as Prozac and Sarafem for treating depression and perinatal depression, on a developing prefrontal cortex. Since fluoxetine works by increasing the levels of serotonin in the brain, the researchers looked at the impact serotonin has on prefrontal cortex development in a fetus. “While […]
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Sandalwood oil by-product prevents prostate cancer development in mice

Extracted from the core of sandalwood trees (santalum album tree), sandalwood oil has been used for many centuries by several cultures throughout the world for perfume, soaps, incense and candles. With its earthy sweet scent, this essential oil also is used in the food industry and topically in various cosmetic preparations. Importantly, this natural oil is known for its health benefits and medicinal applications from antibacterial to anticancer because of its phytochemical constituents. In addition to containing esters, free acids, aldehydes, ketones and santenone, sandalwood oil primarily (90 percent or more) constitutes santalol – equal amounts of two compounds, alpha […]
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‘Furry fruit’ improves mental health – fast Ep. 1175 FEB 2024

A new study found kiwifruit can significantly boost mood and vitality within just 4 days, faster than vitamin C supplements. While both improved mood, participants consuming kiwifruit saw stronger and earlier effects, suggesting synergistic benefits from the whole fruit’s nutrients like fiber, folate, and antioxidants. This highlights the potential of kiwifruit as a readily available and natural way to support mental well-being, even for those with good baseline mental health. #KiwifruitMoodBoost #FastMoodFix #WholeFoodWellness Benjamin D. Fletcher, Jillian J. Haszard, Margreet C. M. Vissers, Tamlin S. Conner. Smartphone survey data reveals the timecourse of changes in mood outcomes following vitamin C […]
Read more » ‘Furry fruit’ improves mental health – fast Ep. 1175 FEB 2024

Magnesium and the Hallmarks of Aging

AbstractMagnesium is an essential ion in the human body that regulates numerous physiological and pathological processes. Magnesium deficiency is very common in old age. Age-related chronic diseases and the aging process itself are frequently associated with low-grade chronic inflammation, called ‘inflammaging’. Because chronic magnesium insufficiency has been linked to excessive generation of inflammatory markers and free radicals, inducing a chronic inflammatory state, we formerly hypothesized that magnesium inadequacy may be considered among the intermediaries helping us explain the link between inflammaging and aging-associated diseases. We show in this review evidence of the relationship of magnesium with all the hallmarks of […]

Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice

Abstract Photoaging, the primary cause of skin aging damage, results from chronic ultraviolet (UV) exposure, leading to dryness and wrinkle formation. Nutritional intervention has emerged as a practical approach for preventing and addressing the effect of skin photoaging. The primary aromatic compound isolated from clove oil, isoeugenol (IE), has antibacterial, anti-inflammatory, and antioxidant qualities that work to effectively restrict skin cancer cell proliferation. This investigation delved into the advantages of IE in alleviating skin photoaging using UVB-irradiated skin fibroblasts and female SKH-1 hairless mouse models. IE alleviated UVB-induced photodamage in Hs68 dermal fibroblasts by inhibiting matrix metalloproteinase secretion and promoting […]
Read more » Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice

Organic compound found in trees could prevent contact lens eye infections

A new study suggests a naturally-occurring material is an effective disinfectant for contact lenses, worn by millions of people worldwide. Microbial keratitis is one of the most serious potential complications for contact lens wearers. It’s an infection of the cornea that is caused by bacteria; the most common being Pseudomonas aeruginosa. Previous studies have found that existing disinfecting solutions are not effective for preventing biofilm, which are clusters of bacteria that attach to the surface of lenses. Hydroquinine, an organic compound found in the bark of some trees, is known to have bacterial killing activity against Pseudomonas aeruginosa and several […]
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Study demonstrates antitumor action of substance present in Brazilian green propolis

Propolis has long been used in traditional medicine and has won attention from the scientific community following proof of its health benefits, which include antioxidant, anti-inflammatory, antimicrobial, antitumor and immunomodulatory properties. Its composition varies according to origin, geographic location, and the bee species that produces it. Researchers affiliated with São Paulo State University (UNESP) in Brazil and the University of Southern Denmark (SDU) set out to analyze Brazilian green propolis, which is produced by the Africanized honeybee (Apis mellifera). Its main component is artepillin C (3,5-diprenyl-4-hydroxycinnamic acid), a phenolic compound primarily found in the resin of Baccharis dracunculifolia, a native […]
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World-first discovery may enable an effective long-term lupus treatment

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment. Published in Nature Communications, the Monash University-led study found a way to reprogram the defective cells of lupus patients with protective molecules from healthy people. Using human cells, the new treatment restores the protective side of the immune system that prevents autoimmunity, which is when the immune system attacks its own cells. The findings relate to the autoimmune disease lupus, a debilitating disease with no cure and limited treatments. But researchers hope this new method, developed in […]
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Effects of Multispecies Probiotic Supplementation on Serum Bone Turnover Markers in Postmenopausal Women with Osteopenia: A Randomized, Double-Blind, Placebo-Controlled Trial

AbstractProbiotics have been found to have beneficial effects on bone metabolism. In this randomized, double-blind, placebo-controlled trial, the effects of multispecies probiotic supplementation on bone turnover markers were evaluated after 12 weeks. Forty postmenopausal women with osteopenia were included and randomly divided into two groups. The intervention group received multispecies probiotics, while the control group received identical placebo sachets daily. The baseline characteristics of both groups were similar. Still, the median serum bone resorption marker C-terminal telopeptide of type I collagen (CTX) was slightly higher in the multispecies probiotic group than in the placebo group (0.35 (0.12, 0.53) vs. 0.16 […]
Read more » Effects of Multispecies Probiotic Supplementation on Serum Bone Turnover Markers in Postmenopausal Women with Osteopenia: A Randomized, Double-Blind, Placebo-Controlled Trial

Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes

Abstract Athletes often take sport supplements to reduce fatigue and immune disturbances during or after training. This study evaluated the acute effects of concurrent ingestion of alkaline water and L-glutamine on the salivary immunity and hormone responses of boxers after training. Twelve male boxing athletes were recruited in this study. During regular training, the participants were randomly divided into three groups and asked to consume 400 mL of alkaline water (Group A), 0.15 g/kg body weight of L-glutamine with 400 mL of water (Group G), and 0.15 g/kg of L-glutamine with 400 mL of alkaline water (Group A+G) at the […]
Read more » Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes

Natural therapy shows promise for dry-eye disease

Researchers at the University of Auckland are running a trial of castor oil as a potential safe and natural treatment for dry-eye disease following a successful pilot study. While exact figures aren’t available for New Zealand, in Australia, it is estimated dry-eye disease affects around 58 percent of the population aged over 50. Advancing age, menopause, increased screen time, contact lens wear are just some of the risk factors for developing dry eye disease. Blepharitis is the most common cause of dry-eye disease, accounting for more than 80 percent of cases. It is a chronic condition with no known cure. […]
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Common food preservative has unexpected effects on the gut microbiome

Food manufacturers often add preservatives to food products to keep them fresh. A primary purpose of these preservatives is to kill microbes that could break down and otherwise spoil the food. Common additives like sugar, salt, vinegar and alcohol have been used as preservatives for centuries, but modern-day food labels now reveal more unfamiliar ingredients such as sodium benzoate, calcium propionate, and potassium sorbate. Bacteria produce chemicals called bacteriocins to kill microbial competitors. These chemicals can serve as natural preservatives by killing potentially dangerous pathogens in food. Lanthipeptides, a class of bacteriocins with especially potent antimicrobial properties, are widely used […]
Read more » Common food preservative has unexpected effects on the gut microbiome

Mind over Matter: Can Mushrooms Boost Your Brain? EP. 1174 FEB 24

The Relationship between Mushroom Intake and Cognitive Performance: An Epidemiological Study in the European Investigation of Cancer—Norfolk Cohort (EPIC-Norfolk) A huge study in the UK followed thousands of people for years, uncovering a delicious secret: eating just one mushroom portion a week (think a small handful) was linked to sharper memory, faster thinking, and better mental control. This brain boost held strong even when considering other healthy habits, hinting that mushrooms might be a hidden weapon against mind fog and even low mood. While more research is needed, reach for those earthy fungi – your brain might just thank you! […]
Read more » Mind over Matter: Can Mushrooms Boost Your Brain? EP. 1174 FEB 24

Active components of ginkgo biloba may improve early cognitive recovery after stroke

Research Highlights: In a study conducted in China, adults treated with 14 days of intravenous injections of ginkgo diterpene lactone meglumine (GDLM) — a combination of biologically active components of ginkgo biloba — after an ischemic (clot-caused) stroke had better cognitive recovery at 14 days and 90 days.IV preparations of ginkgo biloba’s active ingredients are widely used in China as a complementary treatment for ischemic stroke.While oral ginkgo biloba supplements are widely available and marketed in the U.S., gingko biloba is not approved for medicinal use by the U.S. Food and Drug Administration.Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, […]
Read more » Active components of ginkgo biloba may improve early cognitive recovery after stroke

US prescription drug prices are 2.78 times those in other wealthy nations

Prescription drug prices in the U.S. are significantly higher than in other nations, with prices in the U.S. averaging 2.78 times those seen in 33 other nations, according to a new RAND report. The gap between prices in the U.S. and other countries is even larger for brand-named drugs, with U.S. prices averaging 4.22 times those in comparison nations. The RAND study found that prices for unbranded generic drugs — which account for 90% of prescription volume in the U.S. — are about 67% of the average cost in the comparison nations. The new report updates findings from earlier RAND […]
Read more » US prescription drug prices are 2.78 times those in other wealthy nations

Did dementia exist in ancient Greek and Rome?

You might think age-related dementia has been with us all along, stretching back to the ancient world. But a new analysis of classical Greek and Roman medical texts suggests that severe memory loss — occurring at epidemic levels today — was extremely rare 2,000 to 2,500 years ago, in the time of Aristotle, Galen and Pliny the Elder. The USC-led research, published in the Journal of Alzheimer’s Disease, bolsters the idea that Alzheimer’s disease and related dementias are diseases of modern environments and lifestyles, with sedentary behavior and exposure to air pollution largely to blame. “The ancient Greeks had very, […]
Read more » Did dementia exist in ancient Greek and Rome?

Tomato juice’s antimicrobial properties can kill salmonella

Washington, D.C.—Tomato juice can kill Salmonella Typhi and other bacteria that can harm people’s digestive and urinary tract health, according to research published this week in Microbiology Spectrum, a journal of the American Society for Microbiology. Salmonella Typhi is a deadly human-specific pathogen that causes typhoid fever. “Our main goal in this study was to find out if tomato and tomato juice can kill enteric pathogens, including Salmonella Typhi, and if so, what qualities they have that make them work,” said principal study investigator Jeongmin Song, Ph.D., Associate Professor, Department of Microbiology & Immunology, Cornell University.First, the researchers, in laboratory […]
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Beta-Alanine Supplementation in Combat Sports: EP. 1173 JAN 24

Combat athletes, facing explosive bursts and grueling rounds, might find a friend in β-alanine. This amino acid, not a direct performance booster, fuels carnosine, a muscle buffer that fights fatigue. Studies suggest 4-6 grams daily for 4 weeks can improve performance in combat-like bursts (60-240 seconds), potentially boosting strength, power, work capacity, and even recovery. While more research is needed, β-alanine, timed with meals, could be a safe weapon in a combat athlete’s arsenal, helping them push their limits and dominate the ring. #betaalanine #fightfatigue #CarnosinePower Fiandor, E. M., García, J. F., Busto, N., & Roche, E. (2023). β-Alanine Supplementation […]
Read more » Beta-Alanine Supplementation in Combat Sports: EP. 1173 JAN 24

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