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Chicago (June 29, 2024) — Findings from a new mouse study suggest that elenolic acid, a natural compound found in olives, can lower blood sugar levels and promote weight loss. The research could pave the way to the development of safe and inexpensive natural products for managing obesity and type 2 diabetes in people. The researchers found that after just one week, obese mice with diabetes that were given oral elenolic acid weighed significantly less and showed better blood sugar (glucose) regulation than before treatment and compared to control obese mice not receiving elenolic acid. The glucose-lowering effect was comparable with […]
Plant-sourced nitrate proves positive to human health New research from Edith Cowan University (ECU) has found that nitrate from plant sources is associated with a lower risk of mortality while nitrate from other sources such as animal-based foods, processed meat and tap water, is linked to a higher risk of mortality. Nitrate, a compound found in vegetables, meat, and drinking water, has been the subject of debate due to its potential impact on health. Emerging evidence suggests that dietary nitrate may play a role in preventing cardiovascular disease (CVD), dementia, and diabetes. However, concerns about a potential link between nitrate […]
UNIVERSITY PARK, Pa. — Dairy isn’t the only food that’s good for bone health. Prunes may also protect bone structure and strength in postmenopausal women, according to a new study led by Penn State researchers. The findings, published in Osteoporosis International, suggest that daily prune consumption slows the progression of age-related bone loss and reduces the risk of fracture. “This is the first randomized controlled trial to look at three-dimensional bone outcomes with respect to bone structure, geometry and estimated strength,” said Mary Jane De Souza, distinguished professor of kinesiology and physiology at Penn State. “In our study we saw that daily […]
The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments. In a preliminary, randomized, double-blind clinical trial led by Northwestern University and University of Florida scientists, patients who took nicotinamide riboside daily for six months increased their timed walking distance by more than 57 feet, compared to participants who took a placebo. As expected, walking speed declined in those who took a placebo, because peripheral artery disease causes progressive declines in walking performance. “This is a signal that nicotinamide […]
Atlanta, Ga.—Eczema, a skin inflammatory disease that causes dry, itchy and inflamed skin, affects millions worldwide. Eczema is associated with an altered skin microbiome and higher colonization by Staphylococcus aureus. The study, led at New York Medical by postdoctoral fellow Anish R. Maskey, Ph.D., focuses on the natural compound berberine and its impact on eczema exacerbated by S. aureus. The findings, presented at ASM Microbe, shed light on berberine’s ability to inhibit S. aureus colonization and alleviate eczema symptoms without adverse effects. Current treatments often fall short—topical antibiotics can give temporary relief, but risk development of antibiotic resistance, and steroid […]
This research investigates the potential of natural products for cancer treatment, examining both preclinical and clinical studies. The video will explore the mechanisms of action of these promising natural compounds, focusing on specific examples like curcumin and its effects on lung cancer cell growth. We’ll delve into ongoing clinical trials utilizing natural products in cancers like colorectal and ovarian malignancies. Additionally, the video will discuss the potential of dietary components from sources like flaxseed in managing cancer severity. By analyzing research across various cancers, this video aims to provide a comprehensive understanding of the role natural products play in the […]
Plant-derived compounds best known for their antimalarial properties relieve polycystic ovary syndrome, a major public health problem that affects millions of women worldwide. These compounds, called artemisinins, achieve their affect by suppressing ovarian androgen production in multiple rodent models as well as in a small cohort of human patients, according to a new study. The findings not only underscore the versatility of artemisinins but reveal a promising new approach for preventing and treating the disorder. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age. It is characterized by elevated androgen levels (hyperandrogenemia) […]
The benefits of taking extra Ascorbic Acid (AA) while exercising are not well known. This study aims to investigate the effects of AA supplementation on oxidative stress, immune response, and inflammation in healthy women after a single session of high-intensity exercise. In a crossover design, 20 sedentary women (aged 18-22) participated in 30 minutes of vigorous cycling. They were split into two groups: one group received a daily supplement of 1,000 mg of ascorbic acid (1,000AA), while the other group did not receive any supplementation (0AA). This regimen was followed for one week. Blood samples were taken before exercise, immediately […]
UNIVERSITY PARK, Pa. — After women go through menopause, their risk of heart disease increases dramatically. To improve and support heart and blood vessel health among postmenopausal women, researchers at Penn State studied whether beetroot juice can improve how blood vessels function. Results published today (June 10) in Frontiers in Nutrition indicated that daily consumption of beetroot juice by postmenopausal women may improve blood vessel function enough to reduce future heart disease risk. Beetroot juice contains high levels of nitrate, which the body converts to nitric oxide. Nitric oxide helps blood vessels expand, making it easier for blood to flow […]
This research examined the potential of tomato juice to combat bacterial infections. The study found that tomato juice effectively eliminated Salmonella Typhi, the cause of typhoid fever, and uropathogenic E. coli, a bacterium associated with urinary tract infections, within 24 hours. The authors suggest these antimicrobial properties stem from naturally occurring peptides in tomatoes. These findings raise the possibility that incorporating tomato juice into one’s diet could be a valuable tool for managing certain bacterial infections. #tomato #typhoid #UTI Kwon RS, Lee GY, Lee S, Song J.2024.Antimicrobial properties of tomato juice and peptides against typhoidal Salmonella. Microbiol Spectr12:e03102-23.https://doi.org/10.1128/spectrum.0310… tomato juice, […]
Exciting new research suggests urolithin A, a natural compound found in pomegranates, may offer benefits for Alzheimer’s disease. In mouse models, urolithin A improved memory and learning, while also reducing hallmarks of Alzheimer’s like amyloid beta plaques. This effect appears linked to its ability to promote mitophagy, the removal of damaged mitochondria in brain cells. While human trials are needed, these findings highlight the potential of dietary components for neurodegenerative diseases. #UrolithinA #Mitophagy #alzheimers Hou Y, Chu X, Park J-H, et al. Urolithin A improves Alzheimer’s disease cognition and restores mitophagy and lysosomal functions. Alzheimer’s Dement. 2024; 1-22. https://doi.org/10.1002/alz.13847 Urolithin […]
A study by researchers from Nanyang Technological University, Singapore (NTU Singapore) has found that Singaporeans are open to ride air taxis, which are small autonomous aircraft that carry passengers over short distances. Through a study of 1,002 participants, the NTU Singapore team found that almost half (45.7 per cent) say they intend to use this mode of transport when it becomes available, with over one-third (36.2 per cent) planning to do so regularly. According to the findings published online in the journal Technology in Society in April, the intention to take autonomous air taxis is associated with factors such as trust in the AI technology deployed in […]
Orange peels may hold a key to better cardiovascular health, new University of Florida-led research shows. Heart disease is the leading cause of death for men, women and people of most racial and ethnic groups, according to the Centers for Disease Control and Prevention. Recent research has shown that some gut bacteria help develop cardiovascular disease. When they feed on certain nutrients during digestion, gut bacteria produce trimethylamine N-oxide (TMAO). Levels of TMAO can help predict future cardiovascular disease, according to researchers at the Cleveland Clinic. With help from a $500,000 USDA grant, Yu Wang and her team investigated the […]
People who regularly eat fish or take fish oil supplements are getting omega-3 fatty acids, which play a critical role in brain function. Research has long shown a basis in the brain for aggressive and violent behavior, and that poor nutrition is a risk factor for behavior problems. Penn neurocriminologist Adrian Raine has for years been studying whether omega-3 supplementation could therefore reduce aggressive behavior, publishing five randomized controlled trials from different countries. He found significant effects but wanted to know whether these findings extended beyond his laboratory. Now, Raine has found further evidence for the efficacy of omega-3 supplementation by conducting […]
This research examined the effectiveness and safety of Red Yeast Rice Extract (RYR) for lowering cholesterol. They analyzed data from multiple studies and found that RYR extract significantly reduced total and LDL cholesterol levels, which are the “bad” cholesterols. The reductions were comparable to low-dose statins, medications commonly used for cholesterol control. Importantly, there was no increased risk of serious side effects. While more research is needed, this suggests RYR extract may be a safe and effective option for managing cholesterol levels. #cholesterol #redyeastrice #monacolin Trogkanis, E., Karalexi, M. A., Sergentanis, T. N., Kornarou, E., & Vassilakou, T. (2024). Safety […]
This study is reported by Jun Wang’s group from the Institute of Microbiology, Chinese Academy of Sciences, and Yutao Cui’s group from Dr. CUIYUTAO Clinic, Beijing. Since early 2020, the COVID-19 pandemic has had both direct and indirect impacts on health. A decrease in microbial diversity and an increase in opportunistic pathogens were reported in severe COVID-19 patients and were presumed to contribute to the deterioration of host immune functions. The gut microbiomes of infants and children, which are required for the maturation of the human immune system and metabolic processes, have not been thoroughly investigated. The group of Jun […]
A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer’s disease, a new study conducted at the University of Copenhagen concludes. Forgetfulness, difficulty finding words and confusion about time and place. These are some of the most common symptoms of Alzheimer’s disease. Now researchers at the University of Copenhagen have discovered that an ordinary fruit can help. “Our study on mouse models with AD shows that urolithin A, which is a naturally occurring substance in i.a. pomegranates, can alleviate memory problems and other consequences of dementia,” says Vilhelm Bohr, who is Affiliate Professor […]
Women with breast cancer who exclusively ate a whole-foods, plant-based diet lost weight, improved cholesterol levels and other key metabolic factors, had less fatigue, and perceived that they felt sharper mentally and generally more well. The outcomes are from a small study by researchers at the University of Rochester Medical Center and Wilmot Cancer Institute. Study participants were individuals with stage 4 breast cancer, who will be on lifelong treatment. These patients are typically excluded from dietary studies, but with their survivorship numbers growing, it presented an opportunity to make an impact both short- and long-term, said research leader Thomas M. Campbell, MD, an […]
Nearly three-quarters of the United States population receives drinking water that contains fluoride, a practice that began in 1945 to help prevent tooth decay. But recent studies suggest that fluoride exposure can cause harm to a fetus if consumed during pregnancy, a critical period for brain development. A new study, led by researchers at the Keck School of Medicine of USC and funded in part by the National Institutes of Health, analyzed more than 220 mother-child pairs, collecting data on fluoride levels during pregnancy and child behavior at age three. The researchers found that a 0.68 milligram per liter increase […]
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